207737-97-1

Basic information

• Product Name: Taurodeoxycholic acid sodium salt monohydrate
• Synonyms: TAURODEOXYCHOLIC ACID SODIUM SIGMAULTRA;2-([3α,12α-dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid;Taurodeoxycholic acid hydrate sodium salt, 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid;N-(Deoxycholyl)taurine sodium salt, Taurodeoxycholic acid sodium salt, 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt;Sodium taurodeoxycholate hydrate,2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate;2-[[(3alpha,5beta,12alpha)-3,12-Dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid monosodium salt hydrate;Ethanesulfonic acid,2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]aMino]-, sodiuM salt, hydrate (1:1:);3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt
• CAS NO: 207737-97-1
• Molecular Formula: C26H44NO6S.Na.H2O
• Molecular Weight: 539.705
• EINECS: 805-952-8
• Mol File: 207737-97-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 168 °C (dec.)(lit.)
• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: H2O: soluble0.5M, clear, colorless to faintly yellow
• BRN: 3901204
• CAS DataBase Reference: Taurodeoxycholic acid sodium salt monohydrate(CAS DataBase Reference)
• NIST Chemistry Reference: Taurodeoxycholic acid sodium salt monohydrate(207737-97-1)
• EPA Substance Registry System: Taurodeoxycholic acid sodium salt monohydrate(207737-97-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 207737-97-1(Hazardous Substances Data)

Usage

Description

Sodium taurodeoxycholate hydrate is a bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. It has also been used in a study to investigate polymorphic behavior in protein surfactant mixtures.Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane. It has also been used in a study to investigate polymorphic behavior in protein-surfactant mixtures.

Uses

A hydrate form of sodium taurodeoxycholate (T009005), a steroid which rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

General Description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

InChI:InChI=1/C26H45NO6S.Na.H2O/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);;1H2/q;+1;/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;;/m1../s1