207863-56-7Relevant academic research and scientific papers
Efficient synthesis of DOPA analogues in pepticinnamins E via asymmetric catalytic hydrogenation of dehydroamino esters
Sun, De-Qun,Sun, Li,Luo, Min
, p. 1731 - 1734 (2012/08/28)
One practical synthetic procedure with five steps was developed to prepare a series of N-protected-2-(diethoxyphosphoryl)glycinates with good yields, which was treated with aldehydes under mild condition to give different dehydroamino esters with high yields and excellent Z/E selectivity. The subsequently homogeneous enantioselective hydrogenation of the dehydroamino esters affords a series of new DOPA analogues.
C-linked galactosyl serine AFGP analogues as potent recrystallization inhibitors
Liu, Suhuai,Ben, Robert N.
, p. 2385 - 2388 (2007/10/03)
(Chemical Equation Presented) A series of C-linked antifreeze glycoprotein analogues have been prepared to evaluate antifreeze activity as a function of distance between the carbohydrate moiety and polypeptide backbone. The building blocks for these analogues were prepared using either an olefin cross-metathesis or catalytic asymmetric hydrogenation. Analysis of antifreeze protein-specific activity revealed that only analogue 2a (n = 1) was a potent recrystallization inhibitor and thus has potential medical and industrial applications.
Synthesis of the C-analog of 2-acetylamino-2-deoxy-β-D-glucopyranosyl L- and D-serine
Fuchss, Thomas,Schmidt, Richard R.
, p. 753 - 758 (2007/10/03)
Glucosamine was transformed into N-tetrachlorophthaloyl-protected fluoride 5 which gave with allyltrimethylsilane as C-nucleophile in the presence of BF3·OEt2 as catalyst β-C-allyl derivative 6 in good yield. Removal of the TCP group
