207917-52-0

Upstream product

• 583-53-9 2,3-dibromobenzene 
• 116509-98-9 2-bromo-1-(3-hydroxyprop-1-yn-1-yl)benzene 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 207917-51-9 5,8,21,24-Tetrabenzyl-5,8,21,24-tetraaza-tricyclo[26.4.0.0^12,17]dotriaconta-1⁽³²⁾,12⁽¹⁷⁾,13,15,28,30-hexaene-2,10,18,26-tetrayne 
• 207917-53-1 N,N'-dibenzyl-N,N'-bis[3-(2-bromophenyl)prop-2-ynyl]ethylene diamine 

Relevant academic research and scientific papers

Nitrogen substituted cyclic enediynes: Synthesis, thermal reactivity and coniplexation with metal ions

A number of N-substituted cyclic enediynes (azaenediynes) have been synthesized via Pd(0)-catalysed ene-yne coupling followed by N-alkylation. The simplest of them, a 10-membered monocyclic enediyrie 1, underwent Bergman cyclization (BC) at 23°C with a half-life of 72 h. The kinetics of BC slowed down considerably by fusing a benzene ring onto the enediyne. Several novel bis(azaenediyne)s and bis(diazaenediyne)s 3-6 have been synthesized. Their onset temperatures for BC were lowered under metal ion complexation conditions. The Royal Society of Chemistry 2000.

Synthesis and thermal reactivity of a novel macrocyclic enediyne and its copper(II) complex

A novel 24-membered tetraazaenediyne and its copper(II) complex have been synthesized via a Pd(0)-catalysed macrocyclization route. DSC measurements revealed a lowering of onset temperature for Bergman Cyclization upon complexation.