207989-27-3Relevant academic research and scientific papers
Methyltrypsin-catalyzed peptide coupling: Comparison of alkyl ester and guanidinophenyl ester derivatives as acyl donor component
Itoh, Kunihiko,Sekizaki, Haruo,Toyota, Eiko,Tanizawa, Kazutaka
, p. 307 - 319 (2007/10/03)
Methyltrypsin-catalyzed peptide synthesis has been studied by using conventional alkyl ester and p-guanidinophenyl ester derivatives of α-amino acid as the acyl donor component. They were found to be coupled with α- amino acid derivatives (acyl acceptor component) to produce dipeptide. The behavior of methyltrypsin toward both the substrates has been studied.
