207994-95-4

Usage

Physical state

Yellowish-brown liquid

Odor

Sweet, floral

Uses

a. Fragrance ingredient in perfumes and personal care products
b. Synthesis of other organic compounds
c. Reagent in chemical reactions

Safety precautions

a. Toxic if ingested
b. Causes skin and eye irritation
c. High concentrations may cause respiratory irritation and other adverse health effects

Hazardous properties

Toxicity, skin and eye irritant, respiratory irritant at high concentrations

Upstream product

• 2034-41-5 1-(3-aminophenyl)butan-1-one 
• 927-77-5 n-propylmagnesium bromide 
• 207681-67-2 N-methoxy-N-methyl-3-bromobenzamide 
• 114095-73-7 1-(3-bromophenyl)-3-buten-1-ol 

Downstream Products

• 519051-02-6 C₁₀H₁₃BrN₂ 
• 92015-16-2 α-<3-Brom-phenyl>-butylamin 

Relevant academic research and scientific papers

AMINO-5-[4-(DIFLUOROMETHOXY)-PHENYL]-5-PHENYLIMIDAZOLONE COMPOUNDS FOR THE INHIBITION OF BETA-SECRETASE

The present invention provides a 2-amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.

Ruthenium-catalyzed isomerization of homoallylic alcohols in water

Through the catalysis of RuCl2(PPh3)3, the functional groups of homoallylic alcohols are repositioned to give allylic alcohols with controlled regioselectivity. The reaction proceeds most efficiently in an aqueous media. The selectivity in product formation is affected by the reaction temperature and the amount of the catalyst being used. A higher reaction temperature and the use of a smaller amount of the catalyst are preferable for the formation of allylic alcohols. The reaction process was postulated as a tandem olefin migration-allylic rearrangement. Under the same reaction conditions, the functional groups of allylic alcohols undergo allylic rearrangements.