20824-45-7Relevant articles and documents
Simple and efficient synthesis of benzofuran derivatives from tyrosol
Bovicelli, Paolo,Bottaro, Fabrizio,Sappino, Carla,Tomei, Michela,Nardi, Valentina,Proietti Silvestri, Ilaria,Macchi, Beatrice,Frezza, Caterina,Righi, Giuliana
, p. 242 - 248 (2016)
A convenient strategy for the preparation of compounds bearing the benzofuran skeleton starting from tyrosol, a phenol largely present in olive oil production waste, with no biological importance, is reported. A bromination/methoxylation sequence, already described for the synthetic transformation of naturally occurring compounds, was exploited. Depending on the solvent used for the methoxylation reaction together with the presence of a 4-phenol moiety respect to the side chain, benzodihydrofurans or a benzofurans derivative can be obtained.
Synthesis and biological evaluation of gallic acid analogs
Barontini, Maurizio,Proietti Silvestri, Ilaria,Nardi, Valentina,Crisante, Fernanda,Pepe, Gaetano,Pari, Luigi,Gallucci, Francesco,Bovicelli, Paolo,Righi, Giuliana
, p. 674 - 680 (2013/04/10)
A novel and efficient synthesis of pyrogallol moiety through a copper(I)-mediated C-O bond forming reaction is described. In particular, syntheses of 3,4,5-trihydroxyphenethyl alcohol and its methyl derivative are reported. Particular attention to dimethy
New convenient synthesis of iridol. An approach to the synthesis of ubiquinones
Bovicelli, Paolo,Antonioletti, Roberto,Barontini, Maurizio,Borioni, Giorgio,Bernini, Roberta,Mincione, Enrico
, p. 1255 - 1257 (2007/10/03)
A strategy for the synthesis of ubiquinones, in which iridol is the key intermediate, has been developed, together with a new convenient synthesis of iridol (2,3-dimethoxy-5-methylphenol) starting from the easily available 4-methylphenol and using mild conditions and friendly and high-yielding reactions.
