208254-22-2 Usage
Uses
Used in Pharmaceutical Industry:
2,6-Diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile is used as an inhibitor of eEF-2 Kinase for its potential therapeutic applications in treating breast cancer, gliomas, and depression. By targeting eEF-2 Kinase, 2,6-DiaMino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile can modulate cellular processes and pathways involved in the development and progression of these diseases, offering a promising avenue for the development of novel therapeutic strategies.
Used in Chemical Synthesis:
2,6-Diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile is also utilized as a reagent in the synthesis of substituted 3-aryl-2-(2-thiazolyl)acrylonitriles. These synthesized compounds have potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science, due to their diverse chemical properties and potential biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 208254-22-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,8,2,5 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 208254-22:
(8*2)+(7*0)+(6*8)+(5*2)+(4*5)+(3*4)+(2*2)+(1*2)=112
112 % 10 = 2
So 208254-22-2 is a valid CAS Registry Number.
208254-22-2Relevant academic research and scientific papers
MWI-promoted preparation of 4H-thiopyran derivatives through one-pot multi-component reactions
Fan, Xuesen,Wang, Xia,Zhang, Xinying,Li, Xiaoyan,Qu, Guirong
, p. 693 - 695 (2008/09/21)
One-pot reaction of aromatic aldehydes, cyanothioacetamide and malononitrile under microwave irradiation proved to be an efficient way for the synthesis of 2,6-diamino-4-aryl-4H-thiopyran-3,5-dicarbonitriles without any added catalyst.