208466-14-2

Upstream product

• 4064-06-6 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose 
• 193953-69-4 2,3,4,6-tetra-O-benzyl-D-glucopyranosyl diethyl phosphite 
• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 
• 122194-07-4 dimethyl N,N-diisopropylphosphoramidite 

Downstream Products

• 173395-55-6 (3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-5-((((3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran 
• 61474-60-0 cyclohexyl 2,3,4,6-tetra-O-benzyl-D-glucopyranoside 
• 367946-92-7 tert-butyl 2,3,4,6-tetra-O-benzyl-α,β-D-glucopyranoside 
• 84799-76-8 methyl O-(2,3,4,6-tetra-O-benzyl-D-glucopyranosyl)-(1-4)-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 61474-61-1 methyl 2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-D-glucopyranosyl)-α-D-glucopyranoside 

Relevant academic research and scientific papers

Glycosylation of alcohols using glycosyl boranophosphates as glycosyl donors

A novel glycosylation that uses glycosyl boranophosphate triesters as glycosyl donors and trityl cation (Tr+) as an activator was developed. Two types of reactions were studied: (1) the boranophosphate triester was activated with TrNTf2 to react with an alcohol and (2) O-trityl ethers worked as both glycosyl acceptors and Tr+ sources. The latter gave better results and the desired O-glycosylation products were rapidly generated and isolated in moderate to good yields.

Activation of glycosyl phosphites under neutral conditions in solutions of metal perchlorates in organic solvents

Glycosyl phosphites 1-3 derived from glucose are activated under neutral conditions and without the addition of any further promoter in 1 M solutions of LiClO4, Mg(ClO4)2 or Ba(ClO4)2 in ether, CHsub