20847-28-3Relevant academic research and scientific papers
Imine acylation via benzotriazole derivatives: The preparation of enaminones
Katritzky,Fang,Donkor,Xu
, p. 2029 - 2032 (2000)
Metalated ketimines 2a-c are converted into enaminones 3a-p in good to excellent yields by acylbenzotriazoles 1a-f.
Metal-Free Method for Direct Synthesis of Functionalized β-Ketoenamines
Zeng, Xiaobao,Liu, Chulong,Yang, Weiguang,Weng, Yunxiang,Wang, Xinyan,Hu, Yuefei
, p. 3656 - 3661 (2019/03/20)
A new method for direct synthesis of β-ketoenamines was developed by a BF3·OEt2-catalyzed cyclization of 1-iodoalkyne and α-keto acid followed by an amine-mediated ring-opening in one pot. Its metal-free conditions allowed the easy synthesis of those products bearing the transition metal-sensitive functional groups. Its three-component process achieved wide range of functionalized products.
Four-component synthesis of β-enaminone and pyrazole through phosphine-free palladium-catalyzed cascade carbonylation
Shi, Lijun,Xue, Liqin,Lang, Rui,Xia, Chungu,Li, Fuwei
, p. 2560 - 2566 (2015/04/14)
The carbonylative domino synthesis of enaminones and pyrazoles has been performed with the N?N bidentate palladium catalyst to achieve excellent selectivity. These results have confirmed that the carbonylative Sonogashira coupling of iodobenzenes with ter
