208534-68-3Relevant academic research and scientific papers
Uses of quinazolin-2-[(β-propionoyl)isothiocyanate]-4-one as a building block in synthesis of some heterocyclic compounds of expected biological activity
Amine,Eissa,Shaaban,El-Sawy,El-Sayed
, p. 1153 - 1156 (2007/10/03)
The behaviour of quinazaline-2 [(β-propionoyl)isothiocyanate] 1 towards different nucleophilic reagents as phenylhydrazine, aroyl hydrazine, glycine, anthranilic acid (nitrogen nucleaphile), sulphut nucleaphile as a thioglycolic acid and oxygen nucleaphile as ortho amino phenol has been investigated and found that it proceeds via isothiocyanate heterocyclization to furnish non-condensed heterocyclic compounds containing triazoles, oxazole, thiazole and benzoxazale nuclei besides the quinazoline nucleus.
