208641-14-9Relevant academic research and scientific papers
Rhodium-Catalysed Asymmetric Arylation of Pyridylimines
Hu, Yan,Wang, Chenhong,Zhu, Huilong,Xing, Junhao,Dou, Xiaowei
supporting information, p. 531 - 535 (2021/12/22)
The catalytic asymmetric arylation of pyridylimines was developed. A range of pyridylimines reacted with arylboronic acids under rhodium catalysis to produce pyridine-incorporating chiral diarylmethylamines in 46% to 99% yield with 90:10 to 99.5:0.5 er, thus providing a method for the preparation of these important chiral pharmacophores. (Figure presented.).
Aza-Morita-Baylis-Hillman reactions catalyzed by a cyclopropenylidene
Lu, Xun,Schneider, Uwe
supporting information, p. 12980 - 12983 (2016/11/09)
Catalysis using a bis(dialkylamino)cyclopropenylidene (BAC) has been developed, which relies on a formal umpolung activation of Michael acceptor pro-nucleophiles. Various aza-Morita-Baylis-Hillman reactions between aromatic, heteroaromatic, or aliphatic imines and acyclic or cyclic α,β-unsaturated ketones and carboxylic acid derivatives have been catalyzed by a BAC under mild conditions. Functionalities such as unprotected amino and hydroxy groups have been tolerated. The catalyst loading was decreased to 1 mol% without loss of activity. The BAC catalyst was shown to be substantially more active than a cyclic (alkyl)(amino) carbene (CAAC), N-heterocyclic carbenes (NHCs), and P- or N-centered Lewis bases.
A novel method for the synthesis of N-sulfonylaldimines by ZnO as a recyclable neutral catalyst under solvent-free conditions
Hosseini-Sarvari, Mona,Sharghi, Hashem
, p. 2125 - 2130 (2008/02/08)
ZnO acts as an effective catalyst for the rapid synthesis of a range of N-sulfonylaldimines from aromatic aldehydes and sulfonamides under solvent free conditions. The ZnO powder can be reused up to three times after simple washing with distilled water and ethyl acetate.
