208658-63-3Relevant academic research and scientific papers
Asymmetric synthesis of a cytotoxic amide of Telesto riisei
Sankaranarayanan, Sivaraman,Chattopadhyay, Subrata
, p. 1345 - 1350 (2007/10/03)
An efficient synthesis of both the enantiomers of N-(2-phenylethyl)-8- hydroxypentadecacarboxamide using the cytotoxic principles of Telesto riisei has been formulated using cyclohexylideneglyceraldehyde 1 as the chiral template. A non-stereoselective Grignard addition to the aldehyde 1 gave the C-3 epimers of the required chiron, 3-alkylglycerol which were converted to the title compound via a standard sequence of reactions.
