20871-38-9Relevant articles and documents
The Chemistry of Phthalide-3-carboxylic Acid. VI The Stereochemistry of Some 3-Amino(aryl)methylphthalides and the Derived 3-Aryl-4-hydroxy-3,4-dihydroisoquinolin-1(2H)-ones
Collins, Peter R.,Janowski, Wit K.,Prager, Rolf H.
, p. 549 - 560 (2007/10/02)
The isomeric 3-isobenzofuran-1(3H)-ones, of known configuration, have been converted into the corresponding amino and dimethylamino compounds with inversion of configuration, and hence the stereochemistry of these compounds has been
Atropisomerism in o-Arylacetyl-N,N-dimethylbenzamides
Jones, Paul R.,Weisman, Gary R.,Baillargeon, Maurice J.,Gosink, Thomas A.
, p. 3618 - 3620 (2007/10/02)
A series of o-arylacetyl-N,N-dimethylbenzamides, 1-7, being studied as models for chain tautomers, differed markedly in their 1H NMR spectral properties, as a function of the substituents R1-R4.In the two cases where substituents were placed ortho to the amide group, the benzylic protons were anisochronous at ambient temperatures.Reported dynamic 1H NMR results are consistent with concomitant C-N and aryl-CO torsional processes.The 13C carbonyl shifts are compared with those of model compounds.
