208713-50-2

Upstream product

• 152453-71-9 (1'S,4R)-4-(3',3'-bisethylthio-1'-p-methoxybenzyloxypropyl)-2,2-dimethyl-1,3-dioxolane 
• 208713-49-9 (2R,3S)-5,5-Bis-ethylsulfanyl-3-(4-methoxy-benzyloxy)-pentane-1,2-diol 
• 824-94-2 p-methoxybenzyl chloride 
• 67320-20-1 1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3,3-bis-ethylsulfanyl-propan-1-ol 
• 208713-61-5 Toluene-4-sulfonic acid (2R,3S)-5,5-bis-ethylsulfanyl-2-hydroxy-3-(4-methoxy-benzyloxy)-pentyl ester 

Downstream Products

• 159179-11-0 (1E,7Z)-(3S,4S)-1-{(1R,2S,3S)-2-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-3-methyl-cyclohexyl}-2-hydroxymethyl-10-[(2R,5S)-5-((R)-1-methoxy-ethyl)-tetrahydro-furan-2-yl]-4-methyl-deca-1,7-dien-3-ol 
• 1053725-83-9 (3R,5S,6R)-6-Methoxy-5-(4-methoxy-benzyloxy)-hept-1-en-3-ol 
• 159179-12-1 (1E,7Z)-(S)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-1-{(1R,2S,3S)-2-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-3-methyl-cyclohexyl}-10-[(2R,5S)-5-((R)-1-methoxy-ethyl)-tetrahydro-furan-2-yl]-4-methyl-deca-1,7-dien-3-one 
• 159179-13-2 (1E,7Z)-(3S,4S)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-1-{(1R,2S,3S)-2-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-3-methyl-cyclohexyl}-10-[(2R,5S)-5-((R)-1-methoxy-ethyl)-tetrahydro-furan-2-yl]-4-methyl-deca-1,7-dien-3-ol 
• 159179-14-3 (E)-3-{(1R,2S,3S)-2-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-3-methyl-cyclohexyl}-2-((2S,3S,6R)-6-{(E)-3-[(2S,5S)-5-((R)-1-methoxy-ethyl)-tetrahydro-furan-2-yl]-propenyl}-3-methyl-tetrahydro-pyran-2-yl)-prop-2-en-1-ol 
• 159178-96-8 [(2R,3S,5S)-3-(tert-Butyl-diphenyl-silanyloxy)-5-((R)-1-methoxy-ethyl)-tetrahydro-furan-2-yl]-acetic acid methyl ester 
• 159178-95-7 (2R,3S,5S)-5-(tert-Butyl-diphenyl-silanyloxy)-2-methoxy-hept-6-en-3-ol 

Relevant academic research and scientific papers

Synthesis of two new maytansinoid model compounds from carbohydrate precursors

Maytansine (1) is a macrocyclic natural product with significant anti-cancer activity. A derivative (4) of D-glucal is converted to a model compound (10) for the lower periphery of the maytansinoid ring via alkylation at C-6 using an allylic sulfide anion