208767-16-2

Upstream product

• 128373-64-8 (2S,3E)-1,2-isopropylidene-5-O-benzyl-3-pentene-1,2,5-triol 
• 100-39-0 benzyl bromide 
• 79060-23-4 (2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-en-1-ol 
• 128373-66-0 (2S),(E)-5-benzyloxy-3-pentene-1,2-diol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 208767-17-3 tert-Butoxycarbonylamino-acetic acid (E)-(S)-4-benzyloxy-1-(tert-butyl-diphenyl-silanyloxymethyl)-but-2-enyl ester 

Relevant academic research and scientific papers

Synthesis of 5-epi-isofagomine via asymmetric chelate-enolate Claisen rearrangement

Polyhydroxylated piperidines are an interesting class of glycosidase inhibitors. Chelate enolate Claisen rearrangement of N-protected chiral amino acid esters gives rise to γ,δ-unsaturated amino acids, which can be converted to this type of alkaloids. The

Application of the asymmetric chelate-enolate Claisen rearrangement to the synthesis of 5-epi-isofagomine

Chelate-enolate Claisen rearrangement of a N-protected chiral amino acid ester gave rise to a γ,δ-unsaturated amino acid, which could be converted to the potential glycosidase inhibitor 5-epi-isofagomine (9) in a straightforward and a highly stereoselecti