20878-69-7Relevant academic research and scientific papers
Selenium-Catalyzed Carbonylative Synthesis of 3,4-Dihydroquinazolin-2(1 H)-one Derivatives with TFBen as the CO Source
Zhou, Rong,Qi, Xinxin,Wu, Xiao-Feng
supporting information, p. 573 - 577 (2019/08/16)
An efficient and general carbonylative procedure for the synthesis of 3,4-dihydroquinazolin-2(1H)-one from 1-(halomethyl)-2-nitrobenzenes and aryl/alkyl amines have been explored. In this approach, to avoid of using toxic CO gas, a solid and stable CO precursor, TFBen (benzene-1,3,5-triyl triformate), was utilized. With elemental selenium as the catalyst, a variety of aryl/alkyl amines has been tolerated well to afford the corresponding 3,4-dihydroquinazolin-2(1H)-one products in moderate to excellent yields under mild reaction condition.
An efficient synthesis of quinazoline-2,4-dione derivatives with the aid of a low-valent titanium reagent
Shi, Da-Qing,Dou, Guo-Lan,Li, Zheng-Yi,Ni, Sai-Nan,Li, Xiao-Yue,Wang, Xiang-Shan,Wu, Hui,Ji, Shun-Jun
, p. 9764 - 9773 (2008/02/12)
A facile synthetic method using low-valent titanium reagent (TiCl4/Zn system) to promote the novel reductive cyclization of 2-nitrobenzamides and triphosgene is described. Sequentially, a series of quinazoline-2,4-diones were synthesized in goo
