20886-19-5Relevant academic research and scientific papers
Modified mukaiyama reaction for the synthesis of quinoline alkaloid analogues: Total synthesis of 3,3-diisopentenyl-N-methylquinoline-2,4-dione
Zikou, Lamprini C.,Igglessi-Markopoulou, Olga
, p. 1861 - 1866 (2008)
A general synthetic approach, capable of accessing a diverse range of 3,3-disubstituted quinoline-2,4-diones and 1,8-naph-thyridine-2,4-diones via titanium tetrachloride catalyzed C-acylation of silyl ketene acetals is described. The suggested methodological platform is surveyed using different reaction conditions and is applied to the total syntheses of 3,3-diisopentenyl-N-methylquinoline-2,4-dione and 3-demethyl-N-methylatanine.
Iron-Catalyzed Tandem Radical Addition/Cyclization: Highly Efficient Access to Methylated Quinoline-2,4-diones
Sun, Huan,Jiang, Yue,Lu, Ming-Kun,Li, Yun-Yun,Li, Li,Liu, Ji-Kai
, p. 2049 - 2053 (2020/11/09)
A visible-light-induced and iron-catalyzed oxidative radical addition/cyclization cascade reaction of N -(o -cyanoaryl)acrylamides with dimethyl sulfoxide has been developed. The method exhibits a wide substrate scope and an excellent functional-group tol
The Cascade Methylation/Cyclization of ortho-Cyanoarylacrylamides with Dicumyl Peroxide
Yang, Tao,Xia, Wen-Jin,Zhou, Bin,Xin, Yangchun,Shen, Yuehai,Li, Ya-Min
, p. 5749 - 5755 (2019/08/26)
A radical cascade methylation/cyclization of ortho-cyanoarylacrylamides was developed by utilizing dicumyl peroxide as a methylation reagent. This transformation provides a simple and straightforward approach to methylated quinoline-2,4(1H,3H)-diones, and
