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Iso Rizatriptan, also known as Rizatriptan EP Impurity C, is a regioisomer of Rizatriptan. It is a white to off-white solid and is considered a potential impurity in the production of Rizatriptan, a medication used to treat migraines.

208941-96-2

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208941-96-2 Usage

Uses

Used in Pharmaceutical Industry:
Iso Rizatriptan is used as a potential impurity in the production of Rizatriptan for the purpose of ensuring the quality and safety of the final medication. As a regioisomer, it is important to monitor and control its presence during the manufacturing process to maintain the efficacy and purity of Rizatriptan.

Check Digit Verification of cas no

The CAS Registry Mumber 208941-96-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,8,9,4 and 1 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 208941-96:
(8*2)+(7*0)+(6*8)+(5*9)+(4*4)+(3*1)+(2*9)+(1*6)=152
152 % 10 = 2
So 208941-96-2 is a valid CAS Registry Number.

208941-96-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-2-yl]ethanamine

1.2 Other means of identification

Product number -
Other names Rizatriptan impurity C

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:208941-96-2 SDS

208941-96-2Downstream Products

208941-96-2Relevant academic research and scientific papers

Efficient synthesis of impurity-C of antimigraine agent Rizatriptan benzoate

Pramanik, Chinmoy,Bhumkar, Rahul,Karhade, Ganesh,Khairnar, Pravinkumar,Tripathy, Narendra Kumar,Gurjar, Mukund K.

, p. 507 - 511 (2012/08/08)

During the commercial manufacturing of antimigraine drug Rizatriptan benzoate, several impurities are reported to be formed. This present work demonstrates a convergent and short synthesis of the most critical impurity (C) of Rizatriptan, [2-(5-((1H-1,2,4-triazol-1-yl)methyl)-1H-indole-2-yl)-N,N- dimethylethanamine (1)], recently reported in U.S. Pharmacopeia.

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