209160-87-2

Upstream product

• 174855-59-5 1-t-Butoxycarbonyl-4-(2-(1'-(1',2',4'-triazolyl)methyl)phenyl)-piperazine 
• 174855-57-3 tert-butyl 4-(2-formylphenyl)piperazinecarboxylate 
• 179250-28-3 4-(2-(hydroxymethyl)phenyl)piperazine-1-carboxylic acid tert-butyl ester 
• 209160-88-3 1-t-butoxycarbonyl-4-(2-(methanesulfonyloxymethyl)phenyl)-piperazine 

Downstream Products

• 179250-53-4 4(S)-(1(S)-(3,4-Dichlorophenyl)-3-(4-(2-(1'-(1',2',4'-triazolyl)-methyl)phenyl)-1-piperazinyl)-propyl)-3-methyl-2-oxazolidinone 

Relevant academic research and scientific papers

Aryl piperazine melanocortin MC4 receptor agonists

Incorporation of substituted phenyl piperazine privileged structures into a known MC4 specific dipeptoid consensus sequence resulted in a series of potent (EC50=24 nM) and selective MC4-R agonists. We report the SAR of this series of compounds