209216-57-9

Basic information

• Product Name: 3-ForMyl-pyrrole-1-carboxylic acid tert-butyl ester
• Synonyms: 3-ForMyl-pyrrole-1-carboxylic acid tert-butyl ester
• CAS NO: 209216-57-9
• Molecular Formula: C₁₀H₁₃NO₃
• Molecular Weight: 195.21512
• Mol File: 209216-57-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-ForMyl-pyrrole-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ForMyl-pyrrole-1-carboxylic acid tert-butyl ester(209216-57-9)
• EPA Substance Registry System: 3-ForMyl-pyrrole-1-carboxylic acid tert-butyl ester(209216-57-9)

Safety Data

• Hazardous Substances Data: 209216-57-9(Hazardous Substances Data)

Upstream product

• 7126-39-8 pyrrole-3-carboxaldehyde 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 209216-59-1 3-(2-Benzyloxycarbonylamino-2-methoxycarbonyl-ethyl)-pyrrole-1-carboxylic acid tert-butyl ester 
• 209216-60-4 3-(2-Benzyloxycarbonylamino-2-carboxy-ethyl)-pyrrole-1-carboxylic acid tert-butyl ester 
• 209216-56-8 2-amino-3-(1H-pyrrol-3-yl)propanoic acid 

Relevant articles and documents

Synthesis of protected derivatives of 3-pyrrolylalanine

Protected derivatives of 3-pyrrolylalanine (3-PA) have been synthesized starting with N-tri(isopropyl)silylpyrrole. Following formylation and Boc protection, treatment with (±)-N-(benzyloxycarbonyl)-α-phosphonoglycine trimethyl ester provided a fully protected dehydro-3-pyrrolylalanine. Reduction of the double bond and removal of the methyl ester groups yielded 3-PA protected at the α- and pyrrole nitrogens. 3-PA is only transiently stable following N-deprotection.