209223-73-4

Upstream product

• 252209-91-9 (R)-(-)-2-oxo-3-tert-butoxycarbonylamino-5-cyclohexyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepine 
• 13547-70-1 1-chloro-3,3-dimethyl-butan-2-one 
• 73259-81-1 (R)-2-tert-butoxycarbonyl-3-aminopropionic acid 
• 1493-27-2 ortho-nitrofluorobenzene 
• 209223-32-5 (R)-(-)-2-tert-butoxycarbonylamino-3-(2-nitrophenylamino)propionic acid 
• 209223-33-6 (R)-(+)-2-oxo-3-tert-butoxycarbonylamino-1,3,4,5-tetrahydro-2H-1,5-benzodiazepine 
• 74628-31-2 N-1-cyclohexylbenzene-1,2-diamine 
• 108-94-1 cyclohexanone 
• 95-54-5 1,2-diamino-benzene 
• 88-74-4 2-nitro-aniline 
• 6373-71-3 N-cyclohexyl-2-nitroaniline 
• 76387-70-7 (S)-3-amino-2-tert-butoxycarbonylaminopropionic acid 
• 5469-26-1 1-Bromopinacolon 

Downstream Products

• 209219-38-5 (R)-(-)-3-[3-(1-tert-butylcarbonylmethyl-2-oxo-5-cyclohexyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-3-yl]ureido]benzoic acid 
• 343326-73-8 (R)-(-)-1-tert-butylcarbonylmethyl-2-oxo-3-phenoxycarbonylamino-5-cyclohexyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepine 

Relevant academic research and scientific papers

CHOLECYSTOKININ 2 RECEPTOR TARGETED NIR IMAGING AND USE THEREOF

Compounds are described herein where CCK2R targeting ligands are attached to an imaging agent through a linker. The compounds can be used in the detection, diagnosis, imaging and treatment of cancer.

CCK2R-DRUG CONJUGATES

The disclosure provided herein pertains to CCK2R-drug conjugates. In particular, the disclosure pertains to CCK2R-drug conjugates that target the delivery of drugs to a mammalian recipient. Also described are methods of making and using CCK2R-drug conjuga

CHOLECYSTOKININ B RECEPTOR TARGETING FOR IMAGING AND THERAPY

Conjugates are described herein where CCK2R targeting ligands are attached to an active moiety, such as therapeutic agent or an imaging agent, through a linker. The conjugates can be used in the detection, diagnosis, imaging and treatment of cancer.

Calcium salts of 1,5-benzodiazepine derivatives, process for producing the salts and drugs containing the same

Provided are calcium salts of a 1,5-benzodiazepine derivative represented by the following formula (I): (wherein, R1 represents a lower alkyl group, R2 represents a phenyl or cyclohexyl group, and Y represents a single bond or a lowe