209260-22-0

Basic information

• Product Name: (3E,13E)-(7S,8R,9S,16S)-16-(tert-Butyl-diphenyl-silanyloxymethyl)-8-hydroxy-5,5,7,9-tetramethyl-oxacyclohexadeca-3,13-diene-2,6-dione
• Synonyms: (3E,13E)-(7S,8R,9S,16S)-16-(tert-Butyl-diphenyl-silanyloxymethyl)-8-hydroxy-5,5,7,9-tetramethyl-oxacyclohexadeca-3,13-diene-2,6-dione
• CAS NO: 209260-22-0
• Molecular Weight: 590.875
• Mol File: 209260-22-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3E,13E)-(7S,8R,9S,16S)-16-(tert-Butyl-diphenyl-silanyloxymethyl)-8-hydroxy-5,5,7,9-tetramethyl-oxacyclohexadeca-3,13-diene-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (3E,13E)-(7S,8R,9S,16S)-16-(tert-Butyl-diphenyl-silanyloxymethyl)-8-hydroxy-5,5,7,9-tetramethyl-oxacyclohexadeca-3,13-diene-2,6-dione(209260-22-0)
• EPA Substance Registry System: (3E,13E)-(7S,8R,9S,16S)-16-(tert-Butyl-diphenyl-silanyloxymethyl)-8-hydroxy-5,5,7,9-tetramethyl-oxacyclohexadeca-3,13-diene-2,6-dione(209260-22-0)

Safety Data

• Hazardous Substances Data: 209260-22-0(Hazardous Substances Data)

Upstream product

• 209260-20-8 (E)-(6S,7R,8S)-7-Hydroxy-4,4,6,8-tetramethyl-5-oxo-trideca-2,12-dienoic acid (S)-1-(tert-butyl-diphenyl-silanyloxymethyl)-but-3-enyl ester 
• 127793-64-0 (2S)-1-{[tert-butyl(diphenyl)silyl]oxy}pent-4-en-2-ol 
• 106731-74-2 tert-butyl[(2S)-oxiran-2-ylmethoxy]diphenylsilane 
• 106921-60-2 2,2-dimethyl-3-oxopentanal 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 184917-63-3 (S)-2-methyl-hept-6-enal 
• 184917-65-5 4,4-dimethyl-5-oxohept-2-enoic acid 
• 184917-79-1 (E)-4,4-Dimethyl-5-oxo-hept-2-enoic acid tert-butyl ester 
• 209260-18-4 (E)-4,4-Dimethyl-5-oxo-hept-2-enoic acid (S)-1-(tert-butyl-diphenyl-silanyloxymethyl)-but-3-enyl ester 
• 209260-16-2 (S)-1-((1S,5S,7R)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-2-methyl-hept-6-en-1-one 
• 193071-52-2 (S)-2-Methyl-hept-6-en-1-ol 

Relevant articles and documents

The olefin metathesis approach to epothilone A and its analogues

The olefin metathesis approach to epothilone A (1) and several analogues (39-41, 42-44, 51-57, 58-60, 64-65, and 67-69) is described. Key building blocks 6-8 were constructed in optically active form and were coupled and elaborated to olefin metathesis pr