209325-64-4

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 148043-73-6 4,4,5,5,5-pentafluorpentan-1-ol 

Downstream Products

• 252947-52-7 (4,4,5,5,5-pentafluoropentyl)benzylamine 
• 151556-31-9 1,1,1,2,2-pentafluoro-5-iodo-pentane 
• 1383437-60-2 C₅H₆BrF₅ 
• 101615-36-5 (4,4,5,5,5-pentafluoropentyl)iminothiocarbamate 4-methylbenzenesulfonate 
• 1126643-18-2 (4,4,5,5,5-pentafluoropentyl)triphenylphosphonium iodide 
• 1332392-73-0 (4-(benzyloxy)butyl)(4,4,5,5,5-pentafluoropentyl)sulfane 
• 1353007-38-1 4-fluoro-9-{6-[(2-fluoroethyl){3-[(4,4,5,5,5-pentafluoropentyl)sulphonyl]propyl}amino]hexyl}-8-(4-fluorophenyl)-6,7-dihydro-5H-benzo[7]annulen-3-ol 
• 1353007-36-9 4-fluoro-8-(4-fluorophenyl)-9-{6-[{3-[(4,4,5,5,5-pentafluoropentyl)sulphonyl]propyl}(2,2,2-trifluoroethyl)amino]hexyl}-6,7-dihydro-5H-benzo[7]annulen-3-ol 
• 1353007-26-7 9-{6-[(2-fluoroethyl){3-[(4,4,5,5,5-pentafluoropentyl)sulphonyl]propyl}amino]hexyl}-8-(4-fluorophenyl)-6,7-dihydro-5H-benzo[7]annulen-3-ol 
• 1353007-16-5 9-{6-[(2,2-difluoroethyl){3-[(4,4,5,5,5-pentafluoropentyl)sulphonyl]propyl}amino]hexyl}-4-fluoro-8-(4-fluorophenyl)-6,7-dihydro-5H-benzo[7]annulen-3-ol 

Relevant academic research and scientific papers

Mesomorphic phase transition behavior of novel triphenylene compounds possessing fluoroalkylated side chains

This report discusses the effect of fluoroalkyl chain on the mesomorphism. Several homologues of novel triphenylene compounds possessing fluoroalkylated side chains were synthesized. Studies of X-ray diffraction, DSC and texture observations by polarized

Fulvestrant side chain intermediate synthetic method (by machine translation)

The invention relates to a preparation method of fulvestrant side chain intermediates, in particular with five fluorine amyl alcohols in the molecular sieve to the load on the toluene sulfonic acid by the reaction of the five fluorine amyl alcohol tosylates, five fluorine amyl alcohols tosylates in ethanol with the thiourea obtained by the reaction of 4, 4, 5, 5, 5 - pentafluoropropane amyl isothiourea methanesulfonate. The invention avoids the use of acyl chloride, the production process is optimized, thus increasing the reaction yield, and reduces the environmental pollution. (by machine translation)

Tamoxifen and fulvestrant hybrids showed potency as selective estrogen receptor down-regulators

Background: Estrogen receptors (ERs) are an important target for the management of breast cancers. Selective estrogen receptor down-regulators (SERDs) block ER activity, as well as reduce ERα protein levels in cells, and therefore are promising therapeuti

6,7-Dihydro-5H-benzo[7]annulene derivatives, processes for their preparation, pharmaceutical products comprising them and their use for preparing medicaments

The invention relates to selective oestrogen receptor modulators (SERMs) and to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis

6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND THE USE THEREOF FOR PRODUCTION OF MEDICAMENTS

The invention relates to selective oestrogen receptor modulators (SERM) and methods of production thereof, use thereof for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or proph