20933-81-7Relevant articles and documents
A General Procedure for Synthesis of NG-Alkyl, and NG-Aryl-L-Arginines as Potential Nitric Oxide Synthase Inhibitors
Chen, Bor-Cherng,Shiu, Shi,Yang, Ding-Yah
, p. 549 - 553 (2007/10/03)
A general procedure for the synthesis of NG-alkyl, and NG-aryl-L-arginines with relatively high overall yield is reported. The key step involved the coupling of protected L-ornithine 4 with isothiourea 7 to give the fully protected NG-aryl-L-arginine derivative 8. Subsequent deprotection of 8 in acidic condition provided the final target compound 9 with an overall yield of more than 80%.
Synthesis of Guanidino-N-alkylarginines by the Use of Polymeric Pseudoureas
Pundak, Shlomo,Wilchek, Meir
, p. 808 - 809 (2007/10/02)
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