209404-16-0

Upstream product

• 67-56-1 methanol 
• 52249-86-2 2-benzyloxy-4-methoxyacetophenone 

Downstream Products

• 209404-26-2 methyl 3-benzylsulfanyl-2-(2'-tert-butyldimethylsilyloxy-4'-methoxyphenyl)-3-(2''-hydroxy-4''-methoxyphenyl)propanoate 
• 209404-32-0 3-benzylsulfanyl-2-(2'-tert-butyldimethylsilyloxy-4'-methoxyphenyl)-3-(2''-hydroxy-4''-methoxyphenyl)propan-1-ol 
• 209404-25-1 3-Benzylsulfanyl-2-[2-(tert-butyl-dimethyl-silanyloxy)-phenyl]-3-(2-hydroxy-4-methoxy-phenyl)-propionic acid methyl ester 
• 209404-36-4 4-benzylsulfanyl-2'-tert-butyldimethylsilyloxy-4',7-dimethoxyisoflavan 
• 209404-21-7 2-[2-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-3-hydroxy-3-(4-methoxy-2-methoxymethoxy-phenyl)-propionic acid methyl ester 
• 209404-40-0 2-(4-Benzylsulfanyl-7-methoxy-chroman-3-yl)-5-methoxy-phenol 
• 212698-13-0 3-[3,5-Dibromo-4-methoxy-2-(4-methoxy-benzyloxy)-phenyl]-N-(4-{3-[3,5-dibromo-4-methoxy-2-(4-methoxy-benzyloxy)-phenyl]-2-[(E)-hydroxyimino]-propionylamino}-butyl)-2-[(E)-hydroxyimino]-propionamide 
• 212688-12-5 3-[3,5-Dibromo-4-methoxy-2-(4-methoxy-benzyloxy)-phenyl]-N-(4-{3-[3,5-dibromo-4-methoxy-2-(4-methoxy-benzyloxy)-phenyl]-2-oxo-propionylamino}-butyl)-2-oxo-propionamide 
• 212688-10-3 4-[3,5-Dibromo-4-methoxy-2-(4-methoxy-benzyloxy)-phenyl]-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-butyronitrile 
• 212688-08-9 methyl [3,5-dibromo-2-(p-methoxybenzyloxy)-4-methoxyphenyl]acetate 
• 212688-09-0 3,5-dibromo-2-(p-methoxybenzyloxy)-4-methoxyphenylacetic acid 
• 28714-26-3 aerothionin 
• 28687-76-5 3-(3,5-Dibromo-2-hydroxy-4-methoxy-phenyl)-N-(4-{3-(3,5-dibromo-2-hydroxy-4-methoxy-phenyl)-2-[(E)-hydroxyimino]-propionylamino}-butyl)-2-[(E)-hydroxyimino]-propionamide 
• 35353-87-8 methyl (3,5-dibromo-2-hydroxy-4-methoxyphenyl)acetate 

Relevant academic research and scientific papers

PYRANOCHROMENYLPHENOL DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR TREATING METABOLIC SYNDROME OR INFLAMMATORY DISEASE

Provided is a compound of the following Formula (I), a pharmaceutically acceptable salt thereof, or a solvate thereof. Further, provided is a pharmaceutical composition for preventing or treating a metabolic syndrome or an inflammatory disease, including the same. in the formula, R1 is a hydrogen atom, methyl, methoxy, or a halogen atom; R2 is a hydrogen atom; a substituted or unsubstituted straight or branched C1-C6 alkyl group; a halogen atom; a substituted or unsubstituted straight or branched C1-C6 alkoxy group; or a substituted or unsubstituted straight or branched C1-C4 thioalkyl group; R3 and R4 are each independently a hydrogen atom, or a C1-C2 alkyl group; and in the case of the substituted alkyl, the substituted alkoxy, and the substituted thioalkyl, the substituent is a straight or branched C1-C5 alkyl group, a halogen atom, a straight or branched C1-C5 alkoxy group, or a straight or branched C1-C3 thioalkyl group.

PYRANOCHROMENYL PHENOL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR TREATING METABOLIC SYNDROME OR INFLAMMATORY DISEASE

Provided are a pyranochromenyl phenol derivative, a pharmaceutically acceptable salt thereof, or a solvate thereof. Also provided is a pharmaceutical composition for preventing or treating metabolic syndrome or inflammatory disease comprising same. The present invention is efficacious in preventing or treating metabolic syndrome or inflammatory disease and is chemically stable.

Synthesis of isoflavonoids. Enantiopure cis- and trans-6a-hydroxypterocarpans and a racemic trans-pterocarpan

Aldol condensation between phenylacetates and benzaldehydes affords 2,3-diaryl-3-hydroxypropanoates which serve as common precursors to both the first racemic trans-pterocarpan and enantiopure cis- and trans-6a-hydroxypterocarpans.

Direct synthesis of pterocarpans via aldol condensation of phenylacetates with benzaldehydes

Aldol condensation between phenylacetates and benzaldehydes affords 2,3- diaryl-3-hydroxypropanoates which are convened into pterocarpans via stepwise deprotection and cyclization in moderate to high yields.

The first direct synthesis of pterocarpans via aldol condensation of phenylacetates with benzaldehydes

Aldol condensation between phenylacetates and benzaldehydes affords 2,3- diaryl-3-hydroxypropanoates which are converted into pt pans in moderate to high yields.

Syntheses of the marine metabolites verongamine, hemibastadin-2, and aerothionin using the cyano ylide coupling methodology

Syntheses of the marine metabolites verongamine, hemibastadin-2, and aerothionin have been accomplished by a methodology involving the conversion of a carboxylic acid to an acyl cyano phosphorane which may be oxidized to an α,β-diketo nitrile. This strong