209404-18-2

Upstream product

• 209404-16-0 methyl (2-benzyloxy-4-methoxyphenyl)acetate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 212688-07-8 methyl (2-hydroxy-4-methoxyphenyl)acetate 

Downstream Products

• 209404-21-7 2-[2-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-3-hydroxy-3-(4-methoxy-2-methoxymethoxy-phenyl)-propionic acid methyl ester 
• 677717-61-2 methyl 2-(2-tert-butyldimethylsilyloxy-4-methoxyphenyl)-3-(2,4-dimethoxyphenyl)-3-oxopropanoate 
• 209404-26-2 methyl 3-benzylsulfanyl-2-(2'-tert-butyldimethylsilyloxy-4'-methoxyphenyl)-3-(2''-hydroxy-4''-methoxyphenyl)propanoate 
• 209404-32-0 3-benzylsulfanyl-2-(2'-tert-butyldimethylsilyloxy-4'-methoxyphenyl)-3-(2''-hydroxy-4''-methoxyphenyl)propan-1-ol 
• 209404-25-1 3-Benzylsulfanyl-2-[2-(tert-butyl-dimethyl-silanyloxy)-phenyl]-3-(2-hydroxy-4-methoxy-phenyl)-propionic acid methyl ester 
• 209404-36-4 4-benzylsulfanyl-2'-tert-butyldimethylsilyloxy-4',7-dimethoxyisoflavan 
• 209404-40-0 2-(4-Benzylsulfanyl-7-methoxy-chroman-3-yl)-5-methoxy-phenol 
• 677717-62-3 methyl 2-(2-hydroxy-4-methoxyphenyl)-3-(2,4-dimethoxyphenyl)-3-oxopropanoate 
• 479-13-0 coumestrol 

Relevant academic research and scientific papers

Synthesis of isoflavonoids. Enantiopure cis- and trans-6a-hydroxypterocarpans and a racemic trans-pterocarpan

Aldol condensation between phenylacetates and benzaldehydes affords 2,3-diaryl-3-hydroxypropanoates which serve as common precursors to both the first racemic trans-pterocarpan and enantiopure cis- and trans-6a-hydroxypterocarpans.

Direct synthesis of pterocarpans via aldol condensation of phenylacetates with benzaldehydes

Aldol condensation between phenylacetates and benzaldehydes affords 2,3- diaryl-3-hydroxypropanoates which are convened into pterocarpans via stepwise deprotection and cyclization in moderate to high yields.

The first direct synthesis of pterocarpans via aldol condensation of phenylacetates with benzaldehydes

Aldol condensation between phenylacetates and benzaldehydes affords 2,3- diaryl-3-hydroxypropanoates which are converted into pt pans in moderate to high yields.