209409-43-8

Upstream product

• 7699-50-5 (+/-)-3-(2-pyrrolidinyl)-1-propanol 
• 1629-58-9 4-penten-3-one 
• 1026417-23-1 2-(3-Hydroxy-propyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 209409-40-5 2-(3-Oxo-propyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 209409-22-3 2-(3-hydroxypentyl)-3,4-dihydro-5H-pyrrole 
• 209409-51-8 2-(3-hydroxypentyl)pyrrolidine 
• 209409-18-7 3-(3,4-dihydro-2H-pyrrol-5-yl)propan-1-ol 
• 501-53-1 benzyl chloroformate 
• 209409-55-2 2-(3-Hydroxy-pentyl)-pyrrolidine-1-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Umpolung of hemiaminals: Titanocene-catalyzed dehydroxylative radical coupling reactions with activated alkenes

Radical measures: A radical coupling reaction, which is proposed to proceed through in situ chlorination of a hydroxy group by Me3SiCl, is used to form quaternary carbon centers with amino groups in α position. The reaction can be scaled up and

Diastereoselective Synthesis of Cis-3- And 3,5-Alkylpyrrolizidines

Cis-3 and 3,5-substituted pyrrolizidines can be prepared from β-enaminolactones. Substituted pyrrolidinoketones lead to these compounds by an amino reductive annelation with a low diastereomeric excess, but a best access to these azabicycles consists in preparing cis-2,5-disubstituted pyrrolidines which are then transformed into the expected heterocycles.