209416-35-3

Upstream product

• 209416-34-2 4-(2,4,6-trimethylphenyl)-2,3-phthalazin-1-one 
• 108-67-8 1,3,5-trimethyl-benzene 
• 85-44-9 phthalic anhydride 
• 2346-67-0 2-(2,4,6-trimethylbenzoyl)-benzoic acid 

Downstream Products

• 209416-20-6 N-cyclopropylmethyl-N-ethyl-4-(2,4,6-trimethyphenyl)-1-phthalazinamine 
• 209416-21-7 N-cyclopropylmethyl-N-methyl-4-(2,4,6-trimethyphenyl)-1-phthalazinamine 
• 209416-22-8 N-cyclopropylmethyl-N-(2-methoxyethyl)-4-(2,4,6-trimethyphenyl)-1-phthalazinamine 
• 209416-24-0 N-(2'-chlorophenylmethyl)-N-ethyl-4-(2,4,6-trimethyphenyl)-1-phthalazinamine 
• 209416-25-1 N-(4'-chlorophenylmethyl)-N-ethyl-4-(2,4,6-trimethyphenyl)-1-phthalazinamine 
• 209416-26-2 N-(2'-tolylmethyl)-N-ethyl-4-(2,4,6-trimethyphenyl)-1-phthalazinamine 
• 209416-27-3 N-(2'-methoxyphenylmethyl)-N-ethyl-4-(2,4,6-trimethyphenyl)-1-phthalazinamine 
• 209416-28-4 N-(2'-pyridylmethyl)-N-ethyl-4-(2,4,6-trimethyphenyl)-1phthalazinamine 
• 209416-14-8 N-cyclopropylmethyl-N-propyl-4-(2,4,6-trimethylphenyl)-1-phthalazinamine 
• 873216-59-2 4-mesityl-N,N-dipropylphthalazin-1-amine 
• 1393804-92-6 bis{6-(2,4,6-trimethylphenyl)-[1,2,4]triazolo[3,4-a]phthalazin-3-yl}methane 
• 1393804-95-9 2-(2,4,6-trimethylphenyl)-10,11,12,13-tetrahydro-14H-[1]-benzothieno[2',3':4,5]-pyrimido[2,3-a]pyridazin-14-one 
• 1393805-12-3 C₂₀H₂₁N₃O₂ 
• 1393804-90-4 1-[6-(2,4,6-trimethylphenyl)-[1,2,4]triazolo[3,4-a]phthalazin-3-yl]pentane-1,2,3,4,5-pentaol 

Relevant academic research and scientific papers

Synthesis of some biologically active pyrazolylphthalazine derivatives and acyclo-C-nucleosides of 6-(2,4,6-trimethylphenyl)-1,2,4-triazolo[3,4-a]phthalazine

1-Chloro-4-(2,4,6-trimethylphenyl)phthalazine (2) was used as a precursor for preparation of some novel pyrazolylphthalazine derivatives 6-13 and 15-19. Moreover, the acyclonucleosides 20-23 a-e were prepared by the reaction of hydrazinophthalazine deriva

Synthesis and antimicrobial ealuation of some annelated phthalazine deriaties and acyclo C-nucleosides from 1-chloro-4-(2,4,6-trimethylphenyl) phthalazine precursor

A highly efficient and ersatile synthetic approach to the synthesis of annelated phthalazine deriaties iz. 1,2,4-triazolo[3,4-a]phthalazine 11a,b, 14, 18, 19a,b, 29-31, 33, 1,2,4-triazino[3,4-a]phthalazine 25a,b-28, 1,3,5-triazino[4,3-a]phthalazine 22, tetrazolo[5,1-a] phthalazine 23, imidazophthalazine 9a,b,15, and pyrimidinophthlazine 6, 10, 16, 17, 20 is presented. Moreoer, acyclo C -nucleoside and double headed acyclo C-nucleoside of 1,2,4-triazolo[3,4-a]phthalazine 12, 13 were obtained ia heterocyclization reaction of 1-chloro-4-(2,4,6-trimethylphenyl)phthalazine (4) with gluconic acid hydrazide and galactaric acid bis hydrazide, respectiely. The new compounds were synthesized with the objectie of studying their antimicrobial actiity. TUeBITAK.

Isoquinolinamine and phthalazinamine derivatives: corticotropin-releasing factor receptor CRF1 specific ligands

Disclosed are compounds that are highly selective partial agonists or antagonists at human CRF1receptors that are useful in the diagnosis and treatment of treating stress related disorders such as post traumatic stress disorder (PTSD) as well as depression, headache and anxiety. The compounds have the formula or the pharmaceutically acceptable salts thereof wherein Ar, R1, R2, R3, R4and W are various organic and inorganic substituents.