20955-89-9Relevant academic research and scientific papers
Compounds exhibiting thrombopoietin-like activities
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, (2008/06/13)
The compounds of the invention are compounds represented by the following general formula (1): wherein E represents one selected from the group consisting of a methylidyne group and a nitrilo group, R1 represents one selected from the group consisting of optionally substituted aryl groups and optionally substituted heteroaryl groups, R2 represents one selected from the group consisting of a hydrogen atom and alkyl groups, W1 represents an amino acid residue, A represents one selected from the group consisting of a carbonyl group and a sulfonyl group, X1 represents one selected from the group consisting of optionally substituted alkylene groups and optionally substituted alkenylene groups, and p represents 0 or 1; and their pharmacologically acceptable salts, which exhibit thrombopoietin-like activity.
Studies on Potential Juvenile Hormone Analogs: Part I - Synthesis and Physical Studies of Some Heterocyclic Geranyl and Citronellyl Ethers, Their Epoxides, Hydrochlorides and Bromides
Chandra, Umesh,Gupta, Anurag Ateet,Sengupta, A. K.
, p. 528 - 531 (2007/10/02)
Starting from geraniol (I) and citronellol (II), which posses significant JH activity, several heterocyclic ethers (IIIa-h, IVa-h), their epoxides (Va-h, VIa-h), hydrochlorides (VIIa-h and VIIIa-h) and bromides (IX, X) have been synthesised.The structures assigned to the compounds ars supported by their elemental analyses, spectral (IR and PMR) data and physical properties.
