20973-68-6

Basic information

• Product Name: Ethenamine, N,N-dimethyl-2-(4-nitrophenyl)-
• CAS NO: 20973-68-6
• Molecular Formula: C10H12N2O2
• Molecular Weight: 192.217
• Mol File: 20973-68-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethenamine, N,N-dimethyl-2-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethenamine, N,N-dimethyl-2-(4-nitrophenyl)-(20973-68-6)
• EPA Substance Registry System: Ethenamine, N,N-dimethyl-2-(4-nitrophenyl)-(20973-68-6)

Safety Data

• Hazardous Substances Data: 20973-68-6(Hazardous Substances Data)

Upstream product

• 99-99-0 1-methyl-4-nitrobenzene 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 20353-93-9 Gold's reagent 
• 5815-08-7 tert-Butoxybis(dimethylamino)methane 

Downstream Products

• 555-16-8 4-nitrobenzaldehdye 
• 943987-30-2 1,3-diphenyl-4-(4-nitrophenyl)-1H-pyrazole 
• 1422040-89-8 C₄₁H₄₀N₆O₄ 
• 1422041-11-9 C₁₅H₁₄N₄ 
• 64990-07-4 [4-(4-methoxy-phenyl)-1-phenyl-1H-pyrazol-3-yl]-acetic acid 
• 64990-09-6 [4-(4-methoxy-phenyl)-1-phenyl-1H-pyrazol-3-yl]-acetonitrile 
• 64989-94-2 3-bromomethyl-4-(4-chloro-phenyl)-1-phenyl-1H-pyrazole 
• 64989-90-8 4-(4-Aminophenyl)-1-phenyl-pyrazol-3-carbonsaeure-ethylester 
• 64990-08-5 [4-(4-methoxy-phenyl)-1-phenyl-1H-pyrazol-3-yl]-methanol 
• 64989-98-6 4-(4-Nitrophenyl)-1-phenylpyrazol-3-carbonsaeure-ethylester 
• 64989-91-9 4-(4-Chlorphenyl)-1-phenyl-pyrazol-3-carbonsaeure-ethylester 
• 64989-95-3 [4-(4-chloro-phenyl)-1-phenyl-1H-pyrazol-3-yl]-acetonitrile 
• 64989-97-5 3-Chlormethyl-4-(4-methoxyphenyl)-1-phenylpyrazol 
• 64989-93-1 [4-(4-chloro-phenyl)-1-phenyl-1H-pyrazol-3-yl]-methanol 

Relevant articles and documents

HCV NS5A replication complex inhibitors. Part 3

In a recent disclosure,1 we described the discovery of dimeric, prolinamide-based NS5A replication complex inhibitors exhibiting excellent potency towards an HCV genotype 1b replicon. That disclosure dealt with the SAR exploration of the peripheral region of our lead chemotype, and herein is described the SAR uncovered from a complementary effort that focused on the central core region. From this effort, the contribution of the core region to the overall topology of the pharmacophore, primarily vector orientation and planarity, was determined, with a set of analogs exhibiting 50 in a genotype 1b replicon assay.

REACTION OF GOLD'S REAGENT WITH ACTIVATED METHYLENE GROUPS DERIVED FROM ESTERS AND NITROARENES

A series of esters and nitrotoluenes were reacted with Gold's reagent under basic conditions and were found to produce the corresponding dimethylamino methyleneated product in both cases.

Simple method for nitrile formation with chain elongation of active alkyl groups

-