209742-76-7

Basic information

• Product Name: 5(4H)-Oxazolone, 4-(hydroxymethylene)-2-(4-nitrophenyl)-
• Synonyms: 5(4H)-Oxazolone, 4-(hydroxymethylene)-2-(4-nitrophenyl)-
• CAS NO: 209742-76-7
• Molecular Formula: C10H6N2O5
• Molecular Weight: 234.16
• Mol File: 209742-76-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5(4H)-Oxazolone, 4-(hydroxymethylene)-2-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5(4H)-Oxazolone, 4-(hydroxymethylene)-2-(4-nitrophenyl)-(209742-76-7)
• EPA Substance Registry System: 5(4H)-Oxazolone, 4-(hydroxymethylene)-2-(4-nitrophenyl)-(209742-76-7)

Safety Data

• Hazardous Substances Data: 209742-76-7(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 

Relevant articles and documents

Unusual reactions of 2-aryl-4-(N,N-dimethylaminomethylene)-2-oxazolin5-ones with O-nucleophiles: Synthesis of 2-aryl-4-hydi oxymethylene- 2-oxazolin-5-ones

The reactions of 2-aryl-4-(N,N-dimethyIaminomethylene)-2- oxazolin-5-ones 2 with aqueous or ethanolic KOH and sodium ethoxide lead to the formation of 2-aryl-4-hydroxymethylene-2-oxazolin-5ones 4, 1,5-bond remaining unaffected. However, the reactions of 2 with aqueous or methanolic KOH afford methyl 2-acylamino-3-dimethylaminopropenoates 9 along with 4. These observations are explained by the hard-soft acid-base (HSAB) principle. Further, compounds 9 on treatment with POCl3 in pyridine and ethanolic KOH give the corresponding cyclized products 2 and 4, respectively.