209802-87-9Relevant academic research and scientific papers
In vitro evaluation of synthetic heparin-like conjugates comprising different thrombin binding domains
Basten,Dreef-Tromp,De Wijs,Van Boeckel
, p. 1201 - 1206 (1998)
The syntheses of several heparin-like glycoconjugates (i.e., 16a-f) containing identical AT III binding domains (ABD) and spacers but different thrombin binding domains (TBDs) are described. Biological activities of conjugates 16a-f indicate that the thrombin inhibitory activity is mainly determined by the charge density of the TBD moiety.
