20982-28-9

Basic information

• Product Name: 3,5-Diacetoxytoluene
• Synonyms: 3,5-Diacetoxytoluene;5-Methyl-1,3-phenylene diacetate
• CAS NO: 20982-28-9
• Molecular Formula: C₁₁H₁₂O₄
• Molecular Weight: 208.21058
• Mol File: 20982-28-9.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5-Diacetoxytoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Diacetoxytoluene(20982-28-9)
• EPA Substance Registry System: 3,5-Diacetoxytoluene(20982-28-9)

Safety Data

• Hazardous Substances Data: 20982-28-9(Hazardous Substances Data)

Usage

General Description

3,5-Diacetoxytoluene is a chemical compound with the molecular formula C11H14O3. It is an aromatic compound that is commonly used as a precursor for the synthesis of pharmaceuticals and other organic compounds. It is commonly produced through the acetylation of toluene, a process that involves adding acetyl chloride to a mixture of toluene and aluminum chloride. 3,5-Diacetoxytoluene has been studied for its potential use in drug development, particularly for its anti-inflammatory and analgesic properties. Additionally, it is also used as a flavoring agent in the food industry, adding a sweet and floral aroma to various products. However, it is important to note that 3,5-Diacetoxytoluene is a hazardous substance that should be handled with care and in accordance with safety guidelines.

Upstream product

• 504-15-4 orcinol 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 6153-39-5 5-Methylresorcinol monohydrate 

Downstream Products

• 1231750-11-0 5-methyl-4-nitro-1,3-phenylenediacetate 
• 98547-38-7 4-amino-5-methyl-resorcinol 
• 16533-37-2 nitroorcinol 
• 480-67-1 2,6-dihydroxy-4-methyl-benzoic acid 
• 113681-37-1 (E)-2',4'-dibromo-3,3',4,5'-tetramethoxystilbene 
• 113681-38-2 2',4'-dibromo-3,3',4,5'-tetramethoxystilbene 
• 113681-39-3 (E)-2'-bromo-3,3'4,5'-tetramethoxystilbene 
• 10083-24-6 trans-piceatannol 
• 110993-17-4 dimethoxycarbonyloxy-3',5' methoxy-4'' diphenyl-1,2 ethane 
• 110993-16-3 Acetic acid 3-acetoxy-5-[2-(4-methoxy-phenyl)-ethyl]-phenyl ester 
• 33620-66-5 Acetic acid 3-acetoxy-5-[(E)-2-(4-methoxy-phenyl)-vinyl]-phenyl ester 
• 29680-76-0 3,5-diacetoxybenzyl-(triphenyl)phosphonium bromide 
• 90332-29-9 α,β-dihydro-3,5-dihydroxy-4'-methoxystilbene 
• 209746-77-0 3-(benzo[b]furan-5-yl)-6'-tert-butyldimethylsilyloxy-2'-hydroxy-4'-methylpropiophenone 2'-O-(2-O-acetyl-4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-β-D-glucopyranoside) 

Relevant articles and documents

On the metabolites produced by Colletotrichum gloeosporioides a fungus proposed for the Ambrosia artemisiifolia biocontrol; spectroscopic data and absolute configuration assignment of colletochlorin A

Ambrosia artemisiifolia L. is responsible for serious allergies induced on humans. Different approaches for its control were proposed during the COST Action FA1203 “Sustainable management of Ambrosia artemisiifolia in Europe” (SMARTER). Fungal secondary metabolites often show potential herbicidal activity. Three phytotoxins were purified from the fungal culture filtrates of Colletotrichum gloeosporioides, isolated from infected leaves of A. artemisiifolia. They were identified by spectroscopic and chemical methods as colletochlorin A, orcinol and tyrosol (1, 2 and 3). The absolute configuration 6’R to colletochlorin A was assigned for the first time applying the advanced Mosher’s method. When assayed by leaf-puncture on A. artemisiifolia only 1 caused the appearance of large necrosis. The same symptoms were also induced by 1 on ambrosia plantlets associated with plant wilting. On Lemna minor, colletochlorin A caused a clear fronds browning, with a total reduction in chlorophyll content.

HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS

The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.

HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS

The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.