20986-87-2

Basic information

• Product Name: 5a,7a-dimethyl-3,4,5,5a,5b,6,7,7a,9,10,10a,10b,11,12-tetradecahydrocyclopenta[5,6]naphtho[1,2-d]azepine-2,8-dione
• CAS NO: 20986-87-2
• Molecular Formula: C₁₉H₂₇NO₂
• Molecular Weight: 301.4232
• Mol File: 20986-87-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 500.2°C at 760 mmHg
• Flash Point: 177.1°C
• Density: 1.14g/cm³
• Vapor Pressure: 3.87E-10mmHg at 25°C
• Refractive Index: 1.561
• CAS DataBase Reference: 5a,7a-dimethyl-3,4,5,5a,5b,6,7,7a,9,10,10a,10b,11,12-tetradecahydrocyclopenta[5,6]naphtho[1,2-d]azepine-2,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5a,7a-dimethyl-3,4,5,5a,5b,6,7,7a,9,10,10a,10b,11,12-tetradecahydrocyclopenta[5,6]naphtho[1,2-d]azepine-2,8-dione(20986-87-2)
• EPA Substance Registry System: 5a,7a-dimethyl-3,4,5,5a,5b,6,7,7a,9,10,10a,10b,11,12-tetradecahydrocyclopenta[5,6]naphtho[1,2-d]azepine-2,8-dione(20986-87-2)

Safety Data

• Hazardous Substances Data: 20986-87-2(Hazardous Substances Data)

Upstream product

• 53-43-0 dehydroepiandrosterone 
• 7745-40-6 3β-hydroxy-17,17-ethylenedioxo-5-androstene 
• 1044-89-9 androst-4-ene-3-one-17-ethylene ketal 
• 21058-59-3 C₂₁H₃₁NO₃ 
• 59285-18-6 17β-acetoxy-3-hydroximinoandrost-4-ene 
• 21058-55-9 3-aza-17β-acetoxy-A-homo-4α-androsten-4-one 
• 21058-56-0 8-hydroxy-5a,7a-dimethyl-3,4,5,5a,5b,6,7,7a,8,9,10,10a,11,12-tetradecahydrocyclopenta-[5,6]naphtho[1,2-d]azepin-2(10bH)-one 

Downstream Products

• 5044-10-0 3,17α-diaza-A,D-bishomoandrost-4α-ene-4,17-dione 
• 98149-18-9 C₂₆H₃₁N₃O 
• 105431-62-7 (5aR,5bS,7aS,10aS,10bR)-5a,7a-Dimethyl-8-(phenyl-hydrazono)-4,5,5a,5b,6,7,7a,8,9,10,10a,10b,11,12-tetradecahydro-3H-cyclopenta[5,6]naphtho[1,2-d]azepin-2-one 
• 21058-62-8 3-aza-A-homo-4α-androsten-4,17-dione oxime 

Relevant articles and documents

Synthesis of steroidal lactam indoxyl

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Beckmann rearrangement of 3-aza-A-homo-4α-androsten-4,17-dione oxime and 3-oxo-13α-amino-13,17-seco-4-androsten-17-oic 13,17-lactam oxime

Rearragements of 3-aza-A-homo-4α-androsten-4,17-dione oxime produced a mixture of the normal lactam product and the product of a 'second order' cleavage, an unsaturated nitrile. The lactam 3,17α-diaza-A,D-bishomoandrost-4α-ene-4,17-dione was also obtained from the rearrangement of the syn-3-oxo-13α-amino-13,17-seco-4-androsten-17-oic-13,17-lactam oxime. The resolution of syn- and anti-isomers of VIII was effected by column chromatography and their structure was determined by spectral data.