209909-13-7Relevant articles and documents
BICYCLIC DERIVATIVES AS CETP INHIBITORS
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Page/Page column 79-80, (2008/06/13)
The present invention relates to novel compounds of formula (I): or a pharmaceutical composition thereof, with all the variables being defined in the text. The present invention further relates to the use of the compounds herein for treatment of or delay
New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
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, (2008/06/13)
A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
Homocamptothecins: Synthesis and antitumor activity of novel E-ring- modified camptothecin analogues
Lavergne, Olivier,Lesueur-Ginot, Laurence,Rodas, Francesc Pla,Kasprzyk, Philip G.,Pommier, Jacques,Demarquay, Danièle,Prévost, Grégoire,Ulibarri, Gérard,Rolland, Alain,Schiano-Liberatore, Anne-Marie,Harnett, Jeremiah,Pons, Dominique,Camara, José,Bigg, Dennis C. H.
, p. 5410 - 5419 (2007/10/03)
Homocamptothecin (hCPT), a camptothecin (CPT) analogue with a seven membered β-hydroxylactone which combines enhanced plasma stability and potent topoisomerase I (Topo I) mediated activity, is an attractive template for the elaboration of new anticancer a