910903-73-0

Basic information

• Product Name: 4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide
• Synonyms: 4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide
• CAS NO: 910903-73-0
• Molecular Weight: 362.456
• Mol File: 910903-73-0.mol

Chemical Properties

• CAS DataBase Reference: 4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide(910903-73-0)
• EPA Substance Registry System: 4-(5-amino-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide(910903-73-0)

Safety Data

• Hazardous Substances Data: 910903-73-0(Hazardous Substances Data)

Upstream product

• 7154-73-6 1-(2-aminoethyl)pyrrolidine 
• 209968-27-4 4-bromo-N-(2-pyrrolidin-1-ylethyl)benzenesulfonamide 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 910903-69-4 4-(5-nitro-pyrimidin-2-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 

Downstream Products

• 910904-16-4 2-chloro-5-methoxy-N-{2-[4-(2-pyrrolidin-1-yl-ethylsulfamoyl)-phenylamino]-pyrimidin-5-yl}-benzamide 

Relevant articles and documents

2-AMINO-5-SUBSTITUTED PYRIMIDINE INHIBITORS

Compounds having the general structure (A) are provided. The compounds of the invention are capable of inhibiting kinases, such as members of the Src kinase family, Vegfr and various other specific receptor and non-receptor kinases. Formula (I):

PYRIMIDINE COMPOUNDS AND METHODS OF USE

The invention provides pyrimidine compounds having formula (A): The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Src kinase family, and various other specific receptor and non-receptor kinases.