209969-75-5Relevant academic research and scientific papers
Reaction of Paeoniflorin with Lower Alcohols in the Presence of Cation Exchanger
Baltina,Shabieva,Kondratenko,Spirikhin,Baltina
, p. 887 - 890 (2017/10/07)
The reaction of paeoniflorin (PF) with refluxing MeOH in the presence of cation exchanger KU-2-8 (H+) formed a mixture of the 4-O-methyl- and 4-oxo-9-O-methyl ethers (1:1, overall yield 90%) that were separated by chromatography over silica gel. The reaction of PF with EtOH and BuOH under analogous conditions also formed mixtures of the ethyl and butyl ethers from which 4-oxo-9-O-ethyl(butyl) ethers were isolated as the tetra-O-acetates. The structures of the obtained compounds were confirmed using PMR and 13C NMR spectra.
