210037-58-4 Usage
Description
Methyl 5-bromopyrazine-2-carboxylate is a chemical compound with the molecular formula C7H6BrN2O2, belonging to the pyrazine derivative family. It is a brominated ester of 2-carboxypyrazine, characterized by its potential to serve as a building block for synthesizing more complex organic molecules. methyl 5-bromopyrazine-2-carboxylate is recognized for its utility in medicinal chemistry and crop protection, given its capacity to be modified into a variety of biologically active compounds. However, due to its potential hazards, it is crucial to handle this chemical with care and adhere to proper safety protocols.
Uses
Used in Pharmaceutical Industry:
Methyl 5-bromopyrazine-2-carboxylate is used as a synthetic intermediate for the development of pharmaceuticals, leveraging its ability to be incorporated into the molecular structures of various drugs. Its unique properties allow it to contribute to the creation of novel therapeutic agents with potential applications in treating a range of medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, methyl 5-bromopyrazine-2-carboxylate is utilized as a precursor in the synthesis of crop protection agents. Its reactivity and structural features make it suitable for the development of compounds that can protect crops from pests and diseases, thereby enhancing agricultural productivity and crop quality.
Used in Medicinal Chemistry Research:
Methyl 5-bromopyrazine-2-carboxylate is employed as a research tool in medicinal chemistry, where it aids in the exploration of new chemical entities and the optimization of drug candidates. Its versatility in chemical reactions facilitates the discovery of innovative therapeutic agents with improved efficacy and safety profiles.
Used in Organic Synthesis:
As a building block in organic synthesis, methyl 5-bromopyrazine-2-carboxylate is used for the construction of complex organic molecules with diverse applications. Its reactivity and functional groups make it a valuable component in the synthesis of specialty chemicals, materials, and other organic compounds with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 210037-58-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,0,0,3 and 7 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 210037-58:
(8*2)+(7*1)+(6*0)+(5*0)+(4*3)+(3*7)+(2*5)+(1*8)=74
74 % 10 = 4
So 210037-58-4 is a valid CAS Registry Number.
210037-58-4Relevant articles and documents
Synthesis of BACE1 Inhibitors E2609 / E2071 via Oxime-Olefin Cycloaddition following a Process Risk Mitigation Strategy
Benayoud, Farid,Bracke, Markus,Chanda, Arani,Dimopoulos, Paschalis,Fang, Francis G.,Farthing, Christopher N.,Hall, Adrian,Ishida, Tasuku,Kaneko, Toshihiko,Kayano, Akio,Khan, Afzal,Kim, Dae-Shik,Kita, Yoichi,Lu, Lily,Mitasev, Branko,Motoki, Takafumi,Nagai, Mitsuo,Omori, Masayuki,Schnaderbeck, Matthew,Suzuki, Yuichi,Takaishi, Mamoru,Takeda, Kunitoshi,Wakasugi, Kazunori,Watanabe, Yuzo,Yamamoto, Noboru,Yoshizawa, Kazuhiro,Zhang, Huiming
, (2021/08/24)
Process development of E2609 from the preclinical stage to the clinical stage following a process risk mitigation strategy is described here. Key features include a turbo Grignard reaction monitored by in-situ IR, [3 + 2] cycloaddition in water, chemoselective amide coupling via in-situ protection, and a Reformatsky/decarboxylation approach to install a difluoromethyl group. Toward safe and scalable manufacture of E2071, an analog of E2609, a flow-reaction process for trifluoromethylation of aldehydes is presented here.
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
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, (2008/06/13)
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
