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210037-58-4 Usage

General Description

Methyl 5-bromopyrazine-2-carboxylate is a chemical compound with the molecular formula C7H6BrN2O2. It is a derivative of pyrazine and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. methyl 5-bromopyrazine-2-carboxylate is a brominated ester of 2-carboxypyrazine and is typically used as a building block for the creation of more complex organic molecules. Methyl 5-bromopyrazine-2-carboxylate has potential applications in the fields of medicinal chemistry and crop protection due to its ability to be modified into various biologically active compounds. However, it is important to handle this chemical with care and follow appropriate safety protocols due to its potential hazards.

Check Digit Verification of cas no

The CAS Registry Mumber 210037-58-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,0,0,3 and 7 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 210037-58:
74 % 10 = 4
So 210037-58-4 is a valid CAS Registry Number.

210037-58-4 Well-known Company Product Price

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  • Alfa Aesar

  • (H66706)  Methyl 5-bromopyrazine-2-carboxylate, 97%   

  • 210037-58-4

  • 250mg

  • 941.0CNY

  • Detail
  • Alfa Aesar

  • (H66706)  Methyl 5-bromopyrazine-2-carboxylate, 97%   

  • 210037-58-4

  • 1g

  • 2828.0CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017


1.1 GHS Product identifier


1.2 Other means of identification

Product number -
Other names QC-489

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:210037-58-4 SDS

210037-58-4Relevant articles and documents

Synthesis of BACE1 Inhibitors E2609 / E2071 via Oxime-Olefin Cycloaddition following a Process Risk Mitigation Strategy

Benayoud, Farid,Bracke, Markus,Chanda, Arani,Dimopoulos, Paschalis,Fang, Francis G.,Farthing, Christopher N.,Hall, Adrian,Ishida, Tasuku,Kaneko, Toshihiko,Kayano, Akio,Khan, Afzal,Kim, Dae-Shik,Kita, Yoichi,Lu, Lily,Mitasev, Branko,Motoki, Takafumi,Nagai, Mitsuo,Omori, Masayuki,Schnaderbeck, Matthew,Suzuki, Yuichi,Takaishi, Mamoru,Takeda, Kunitoshi,Wakasugi, Kazunori,Watanabe, Yuzo,Yamamoto, Noboru,Yoshizawa, Kazuhiro,Zhang, Huiming

, (2021/08/24)

Process development of E2609 from the preclinical stage to the clinical stage following a process risk mitigation strategy is described here. Key features include a turbo Grignard reaction monitored by in-situ IR, [3 + 2] cycloaddition in water, chemoselective amide coupling via in-situ protection, and a Reformatsky/decarboxylation approach to install a difluoromethyl group. Toward safe and scalable manufacture of E2071, an analog of E2609, a flow-reaction process for trifluoromethylation of aldehydes is presented here.



, (2008/06/13)

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

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