21011-86-9

Basic information

• Product Name: 4-Piperidinone, 1,2,6-triphenyl-
• CAS NO: 21011-86-9
• Molecular Formula: C23H21NO
• Molecular Weight: 327.426
• Mol File: 21011-86-9.mol

Chemical Properties

• CAS DataBase Reference: 4-Piperidinone, 1,2,6-triphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinone, 1,2,6-triphenyl-(21011-86-9)
• EPA Substance Registry System: 4-Piperidinone, 1,2,6-triphenyl-(21011-86-9)

Safety Data

• Hazardous Substances Data: 21011-86-9(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 1833-53-0 2-(Trimethylsilyloxy)propene 
• 100-52-7 benzaldehyde 
• 538-51-2 benzylidene phenylamine 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 1896-62-4 (E)-benzalacetone 

Downstream Products

• 62-53-3 aniline 
• 538-58-9 1,5-diphenyl-1,4-pentadiene-3-one 

Relevant articles and documents

Bismuth triflate-catalyzed three-component Mannich-type reaction

Bismuth triflate catalyzes the Mannich-type reaction of a variety of in situ generated aldimines using aldehydes, anilines, and silyl enol ethers in a three-component reaction. The reaction proceeds rapidly and affords the corresponding protected β-amino

Catalytic imino Diels-Alder reaction by triflic imide and its application to one-pot synthesis from three components

An imino Diels-Alder reaction of 2-siloxydienes with aldimines catalyzed by triflic imide (Tf2NH; 0.1～10 mol % amount) has been developed leading to substituted piperidin-4-ones. Tf2NH catalyst is compatible with basic functions, such as pyridine and indole rings in the imino Diels-Alder reaction. Furthermore, X-ray crystallographic analysis indicates that trans-2,6-diphenyl-4-piperidinone 4a obtained by this reaction has a unique conformation in the solid state.

Stereoselective synthesis of meso- and cis-2,6-diarylpiperidin-4-ones catalyzed by L-proline

A convenient stereoselective preparation of meso- and cis-2,6- diarylpiperidin-4-ones has been developed by aza-Diels-Alder reaction catalyzed by L-proline from simple and commercially available starting materials. Georg Thieme Verlag Stuttgart.

Proline-catalyzed imino-Diels-Alder reactions: Synthesis of meso-2,6-diaryl-4-piperidones

Amine-catalyzed imino-Diels-Alder reactions of acyclic α,β- unsaturated ketones with imines have been developed. L-Proline catalyzed the in situ generation of 2-amino-1,3-butadienes to provide a stereoselective synthesis of meso-2,6-diaryl-4-piperidones i

An imino-Diels-Alder route to meso-2,6-disubstituted-4-piperidones

A convenient stereoselective preparation of meso-2,6-disubstituted-4- piperidones has been developed by imino-Diels-Alder reaction of 2-amino-1,3-butadienes with imines in the presence of catalytic amount of Cu(TfO)2.