21018-39-3Relevant academic research and scientific papers
One-pot synthesis of N-allylthioureas using supported reagents
Aoyama, Tadashi,Murata, Sumiko,Nagata, Yasutaka,Takido, Toshio,Kodomari, Mitsuo
, p. 4875 - 4878 (2005)
A simple and efficient method has been developed for the synthesis of N-allylthioureas from allylic bromides in one-pot by using a supported reagents system, KSCN/SiO2-RNH3OAc/Al2O3, in which allyl bromide reacts first with KSCN/SiO2 and the product, allyl isothiocyanate, reacts with RNH3OAc/Al2O3 to give the final product, N-allylthiourea, in good yield.
Regioselectivity of the Reaction of Methallyl Isothiocyanate with Monosubstituted Hydrazines
Richter, C.,Klatt, K.,Feuerer, A.,Schulze, K.
, p. 60 - 66 (2007/10/02)
Methallyl isothiocyanate 1 reacts with substituted aryl hydrazines to 1,4- respectively 2,4-disubstituted thiosemicarbazides 4 and 5 in dependence on the reaction conditions and the nature of the aryl group.The influence of the substituents is discussed.T
