21026-75-5

Basic information

• Product Name: Benzeneethanamine, a-methyl-N-(2-phenylethyl)-
• Synonyms: Diphenethylamine,a-methyl- (7CI,8CI)
• CAS NO: 21026-75-5
• Molecular Formula: C₁₇H₂₁N
• Molecular Weight: 275.8163
• Mol File: 21026-75-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 362.4°Cat760mmHg
• Flash Point: 168.8°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 1.94E-05mmHg at 25°C
• CAS DataBase Reference: Benzeneethanamine, a-methyl-N-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanamine, a-methyl-N-(2-phenylethyl)-(21026-75-5)
• EPA Substance Registry System: Benzeneethanamine, a-methyl-N-(2-phenylethyl)-(21026-75-5)

Safety Data

• Hazardous Substances Data: 21026-75-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H21N.ClH/c1-15(14-17-10-6-3-7-11-17)18-13-12-16-8-4-2-5-9-16;/h2-11,15,18H,12-14H2,1H3;1H

Upstream product

• 64-04-0 phenethylamine 
• 103-79-7 1-phenyl-acetone 
• 38084-50-3 Phenylacetic acid β-phenylisopropylamide 
• 141381-81-9 phenylethylamide of o-nitrophenylsulfonic acid 
• 60-12-8 2-phenylethanol 
• 698-87-3 3-phenyl-2-propanol 
• 851219-33-5 N-(1-methyl-2-phenyl-ethyl)-2-nitro-N-phenethyl-benzenesulfonamide 

Downstream Products

• 95439-68-2 N-Phenethyl-N-( 1-methyl-phenethyl )-bernsteinsaeure-ethylester-amid 
• 95003-77-3 4-< N-Phenethyl-N-( 1-methyl-phenethyl )-amino>-butan-1-ol 

Relevant articles and documents

The facile preparation of primary and secondary amines via an improved Fukuyama-Mitsunobu procedure. Application to the synthesis of a lung-targeted gene delivery agent

An efficient modification of the Fukuyama-Mitsunobu procedure has been developed whereby primary or secondary amines can be synthesized from alkyl alcohols and the corresponding nosyl-protected/activated amine. Most importantly, the use of the DTBAD and diphenylpyridinylphosphine, as Mitsunobu reagents, generates reaction by-products that can be easily removed, providing a remarkably clean product mixture. This improved technique was implemented in the synthesis of a complex lipopeptide designed to target α 9β1-integrin proteins predominant on upper airway epithelial cells. The Royal Society of Chemistry 2005.