21026-97-1Relevant academic research and scientific papers
Synthesis and 31P chemical shift identification of tripeptide active site models that represent human serum acetylcholinesterase covalently modified at serine by certain organophosphates.
Thompson,Suarez,Rodriguez
, p. 1325 - 1332 (2007/10/03)
Most organophosphorus (OP) insecticides impart their toxic action via inhibition of cholinesterases by reacting at an essential serine hydroxyl group. The inhibition process is dependent upon the reactivity, stereochemistry, leaving group, and the mechani
