21032-39-3Relevant academic research and scientific papers
Sonogashira coupling reactions in biodegradable ionic liquids derived from nicotinic acid
Harjani, Jitendra R.,Abraham, Theodore J.,Gomez, Alwyn T.,Garcia, M. Teresa,Singer, Robert D.,Scammells, Peter J.
experimental part, p. 650 - 655 (2010/08/22)
The biodegradable ionic liquids, 3-butoxycarbonyl-1-methylpyridinium bis(trifluoromethanesulfonyl)imides (1a-d), have been evaluated as solvents for copper- and phosphine-free Sonogashira coupling reactions. The stability of these ionic liquids toward basic conditions was analysed in order to further probe their utility for transition metal catalyzed reactions which require the presence of a base.
Biodegradable pyridinium ionic liquids: Design, synthesis and evaluation
Harjani, Jitendra R.,Singer, Robert D.,Garcia, M. Teresa,Scammells, Peter J.
experimental part, p. 83 - 90 (2010/04/22)
A range of ionic liquids (ILs) with a pyridinium cation were synthesised and their biodegradability was evaluated using the CO2 Headspace test (ISO 14593). ILs bearing an ester side chain moiety were prepared from either pyridine or nicotinic acid and showed high levels of biodegradation under aerobic conditions and can be classified as 'readily biodegradable'. In contrast, pyridinium ILs with alkyl side chains showed significantly lower levels of biodegradability in the same test. The utility of the biodegradable IL 6c as a reaction solvent for the Diels-Alder reaction was also investigated.
