210346-60-4Relevant articles and documents
Synthesis and antitumor activity of ring A- and F-modified hexacyclic camptothecin analogues
Sugimori, Masamichi,Ejima, Akio,Ohsuki, Satoru,Uoto, Kouichi,Mitsui, Ikuo,Kawato, Yasuyoshi,Hirota, Yasuhide,Sato, Keiki,Terasawa, Hirofumi
, p. 2308 - 2318 (2007/10/03)
Nineteen ring A- and F-modified hexacyclic analogues of camptothecin were synthesized by Friedlander condensation of appropriately substituted bicyclic amino ketones with tricyclic ketone and were evaluated for cytotoxicity and topoisomerase I inhibitory