21047-77-8Relevant academic research and scientific papers
REGENERATION OF AMINO COMPOUNDS FROM THE 2,4,6-TRINITROPHENYL DERIVATIVES BY TREATMENT WITH HYDRAZINE
Takahashi, Seitaro,Yamamura, Takaki,Kamo, Masaharu,Satake, Kazuo
, p. 127 - 130 (1984)
2,4,6-Trinitrophenylalanine gave free alanine and 1-hydroxy-4,6-dinitrobenzotriazole by treating with aqueous solution of hydrazine at pH 7-9 and 30 deg C.Applying the reaction to partially trinitrophenylated derivative of lima bean trypsin inhibitor, the fully active protein could be regenerated almost quantitatively.
The ambident reactivity of aromatic amines in their reactions with N-2-(2,4,6-trinitrophenyl)-4,6-dinitrobenzotriazole-1-oxide, a new heterocyclic super-electrophile
Buncel, Erwin,Renfrow, Richard A.,Strauss, Michael J.
, p. 1690 - 1692 (2007/10/02)
Reaction between the title compound 2 and 2,6-dimethylaniline, or N,N-dimethylaniline, gives rise to spectrally observable Meisenheimer type ?-complexes in which bonding has occurred between the para carbon of the aromatic amine and the benzotriazole moiety of 2; however, aniline reacts at the picryl moiety to give the product of displacement 5, via the aniline nitrogen as the nucleophilic atom.
