REGENERATION OF AMINO COMPOUNDS FROM THE 2,4,6-TRINITROPHENYL DERIVATIVES BY TREATMENT WITH HYDRAZINE

Article abstract of DOI:10.1246/cl.1984.127

2,4,6-Trinitrophenylalanine gave free alanine and 1-hydroxy-4,6-dinitrobenzotriazole by treating with aqueous solution of hydrazine at pH 7-9 and 30 deg C.Applying the reaction to partially trinitrophenylated derivative of lima bean trypsin inhibitor, the fully active protein could be regenerated almost quantitatively.