21048-87-3Relevant academic research and scientific papers
Synthesis and antimicrobial activity of N-alkyl and N-aryl piperazine derivatives
Chaudhary, Preeti,Kumar, Rupesh,Verma, Akhilesh K.,Singh, Devender,Yadav, Vibha,Chhillar, Anil K.,Sharma,Chandra, Ramesh
, p. 1819 - 1826 (2007/10/03)
A series of substituted piperazine derivatives have been synthesized and tested for antimicrobial activity. The antibacterial activity was tested against Staphylococcus aureus (MTCCB 737), Pseudomonas aeruginosa (MTCCB 741), Streptomyces epidermidis (MTCCB 1824) and Escherichia coli (MTCCB 1652), and antifungal activity against Aspergillus fumigatus, Aspergillus flavus and Aspergillus niger. All synthesized compounds showed significant activity against bacterial strains but were found to be less active against tested fungi. In vitro toxicity tests demonstrated that compounds 4d and 6a showed very less toxicity against human erythrocytes.
Phenylpiperazine-Based Radiopharmaceutical for Brain Imaging. 3. Synthesis and Evaluation of Radioiodinated 1-Alkyl-4-phenylpiperazines
Hanson, Robert N.,Hassan, Mohamad
, p. 29 - 34 (2007/10/02)
As part of our program in radiopharmaceutical chemistry we have prepared and evaluated a series of radioiodinated 1-alkyl-4-phenylpiperazines as potential brain-imaging agents.The compounds were chosen on the basis of their synthetic versatility, activati
