210569-79-2

Upstream product

• 249757-17-3 [3-(7-bromo-3H-indol-3-yl)propionylamino]acetic acid methyl ester 
• 210889-34-2 3-(7-bromo-3H-indol-3-yl)propionic acid ethyl ester 
• 210569-70-3 3-(7-bromo-3H-indol-3-yl)propionic acid 
• 115666-21-2 7-bromo-1 H-indole-3-carbaldehyde 
• 51417-51-7 7-bromo-1H-indole 
• 39959-54-1 3-bromobenzylamine hydrochloride 
• 210569-72-5 [3-(7-bromo-3H-indol-3-yl)propionylamino]acetic acid 

Relevant academic research and scientific papers

Synthetic studies towards the synthesis of western and eastern chloropeptin I, II subunits

The western subunit (16-membered ring) was synthesized by the intramolecular SNAr reaction while the first 16-membered ring compound was obtained as a model of the eastern subunit via an intramolecular Ni0 mediated coupling reaction.

The first synthesis of simplified 16- and 17-membered ring macropolypeptides containing the phenyl-indole system of Kistamycin and Chloropeptin I, II

The synthesis of simplified 16- and 17-membered ring macropolypeptides was achieved by Ni°mediated carbon-carbon ring closure of properly substituted linear precursors.