210585-23-2

Upstream product

• 141-82-2 malonic acid 
• 2405-59-6 N-(2-phenylethyl)-4-methoxyaniline 

Downstream Products

• 210585-39-0 N-(4-Methoxy-phenyl)-N-phenethyl-malonamic acid (1R,2S,3S,4R)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester 
• 210585-57-2 1-(4-Methoxy-phenyl)-2-oxo-4-phenyl-pyrrolidine-3-carboxylic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester 
• 210585-68-5 1-(4-Methoxy-phenyl)-2-oxo-4-phenyl-pyrrolidine-3-carboxylic acid (1R,2S,3S,4R)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester 
• 174618-44-1 (R)-1-(4-methoxyphenyl)-4-phenylpyrrolidin-2-one 
• 174618-43-0 (S)-1-(4-methoxyphenyl)-4-phenylpyrrolidin-2-one 
• 174618-57-6 2-Diazo-N-(4-methoxy-phenyl)-N-phenethyl-malonamic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester 
• 174692-21-8 2-Diazo-N-(4-methoxy-phenyl)-N-phenethyl-malonamic acid (1R,2S,3S,4R)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester 
• 62624-45-7 (S)-4-phenyl-1-tosylpyrrolidin-2-one 
• 71657-88-0 (4R)-4-phenyl-2-pyrrolidone 
• 210585-32-3 N-(4-Methoxy-phenyl)-N-phenethyl-malonamic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester 

Relevant academic research and scientific papers

The Rh2(OAc)4 catalysed C-H insertion in chiral ester diazoanilides

The Rh2(OAc)4-catalysed C-H insertion in chiral ester diazoanilides was investigated and was found to yield 4-substituted 2-pyrrolidinones with moderate to high e.e. (37-98%) after decarbalkoxylation. Electronic effects were found to oppose steric effects in influencing the enantioselectivity of the reaction in N-arylethyl diazoanilides.