210585-41-4

Upstream product

• 135557-18-5 (4S)-4,7,7-trimethyl-3-exo-(1-naphthyl)bicyclo<2.2.1>heptan-2-exo-ol 
• 210585-28-7 N-(4-Methoxy-phenyl)-N-[2-(4-nitro-phenyl)-ethyl]-malonamic acid 

Downstream Products

• 210585-70-9 1-(4-Methoxy-phenyl)-4-(4-nitro-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid (1R,2S,3S,4R)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester 
• 174618-62-3 2-Diazo-N-(4-methoxy-phenyl)-N-[2-(4-nitro-phenyl)-ethyl]-malonamic acid (1R,2S,3S,4R)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester 

Relevant academic research and scientific papers

The Rh2(OAc)4 catalysed C-H insertion in chiral ester diazoanilides

The Rh2(OAc)4-catalysed C-H insertion in chiral ester diazoanilides was investigated and was found to yield 4-substituted 2-pyrrolidinones with moderate to high e.e. (37-98%) after decarbalkoxylation. Electronic effects were found to oppose steric effects in influencing the enantioselectivity of the reaction in N-arylethyl diazoanilides.